Morphine Sulfate Injection shortage
Current 24 presentations · 5 manufacturers · first FDA posting 2017-10-31 · last update 2026-10-15
Manufacturers: Amphastar Pharmaceuticals, Inc., Fresenius Kabi USA, LLC, Hikma Pharmaceuticals USA, Inc., Hospira, Inc., a Pfizer Company, Piramal Critical Care Inc.
Stated reasons (per FDA): Demand increase for the drug; Discontinuation of the manufacture of the drug; Other
Presentations
| Presentation | Manufacturer | Status | Reason | Notes (FDA) | Dates |
|---|---|---|---|---|---|
| Morphine Sulfate, Injection, 1 mg/1 mL (NDC 76329-1912-1) | Amphastar Pharmaceuticals, Inc. | Current Available |
— | Posted 12/06/2018 Updated 10/05/2026 | |
| Morphine Sulfate, Injection, 10 mg/1 mL (NDC 63323-451-01) | Fresenius Kabi USA, LLC | Current Available |
— | Check wholesalers for inventory | Posted 10/31/2017 Updated 10/15/2026 |
| Morphine Sulfate, Injection, 2 mg/1 mL (NDC 63323-452-01) | Fresenius Kabi USA, LLC | Current Available |
— | Check wholesalers for inventory | Posted 10/31/2017 Updated 10/15/2026 |
| Morphine Sulfate, Injection, 4 mg/1 mL (NDC 63323-454-01) | Fresenius Kabi USA, LLC | Current Unavailable |
Other | Next release November 2026. Check wholesalers for inventory. | Posted 10/31/2017 Updated 10/15/2026 |
| Morphine Sulfate, Injection, 5 mg/1 mL (NDC 63323-455-01) | Fresenius Kabi USA, LLC | Current Unavailable |
Demand increase for the drug | Estimated recovery: TBD | Posted 10/31/2017 Updated 10/15/2026 |
| Morphine Sulfate, Injection, 2 mg/1 mL (NDC 76045-004-11) | Fresenius Kabi USA, LLC | Current Available |
— | Check wholesalers for inventory | Posted 10/31/2017 Updated 10/15/2026 |
| Morphine Sulfate, Injection, 4 mg/1 mL (NDC 76045-005-11) | Fresenius Kabi USA, LLC | Current Available |
— | Check wholesalers for inventory | Posted 10/31/2017 Updated 10/15/2026 |
| Duramorph, Injection, 1 mg/1 mL (NDC 0641-6019-10) | Hikma Pharmaceuticals USA, Inc. | Current Available |
— | Additional lots are scheduled to be manufactured. Product will be made available as it is released. | Posted 11/03/2017 Updated 10/14/2026 |
| Duramorph, Injection, .5 mg/1 mL (NDC 0641-6020-10) | Hikma Pharmaceuticals USA, Inc. | Current Available |
— | Additional lots are scheduled to be manufactured. Product will be made available as it is released. | Posted 11/03/2017 Updated 10/14/2026 |
| Infumorph 200 (Preservative-Free Morphine Sulfate Sterile Solution), Injection, 10 mg/1 mL (NDC 0641-6039-01) | Hikma Pharmaceuticals USA, Inc. | Current Unavailable |
Demand increase for the drug | Additional lots will be available in the November 2026 timeframe. Product will be made available as it is released. | Posted 11/03/2017 Updated 10/14/2026 |
| Infumorph 500 (Preservative-Free Morphine Sulfate Sterile Solution), Injection, 25 mg/1 mL (NDC 0641-6040-01) | Hikma Pharmaceuticals USA, Inc. | Current Available |
— | Additional lots are scheduled to be manufactured. Product will be made available as it is released. | Posted 11/03/2017 Updated 10/14/2026 |
| Morphine Sulfate, Injection, 4 mg/1 mL (NDC 0641-6125-25) | Hikma Pharmaceuticals USA, Inc. | Current Available |
— | Additional lots are scheduled to be manufactured. Product will be made available as it is released. | Posted 11/03/2017 Updated 10/14/2026 |
| Morphine Sulfate, Injection, 8 mg/1 mL (NDC 0641-6126-25) | Hikma Pharmaceuticals USA, Inc. | Current Available |
— | Additional lots are scheduled to be manufactured. Product will be made available as it is released. | Posted 11/03/2017 Updated 10/14/2026 |
| Morphine Sulfate, Injection, 10 mg/1 mL (NDC 0641-6127-25) | Hikma Pharmaceuticals USA, Inc. | Current Available |
— | Additional lots are scheduled to be manufactured. Product will be made available as it is released. | Posted 11/03/2017 Updated 10/14/2026 |
| Morphine Sulfate, Injection, 2 mg/1 mL Syringes (NDC 0409-1890-01) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted 10/31/2017 Updated 10/08/2026 | |
| Morphine Sulfate, Injection, 2 mg/1 mL (NDC 0409-1890-23) | Hospira, Inc., a Pfizer Company | Current Limited Availability |
Other | Limited Supply Available. Next Delivery: November 2026; Estimated Recovery: December 2026; Shortage per Manufacturer: Manufacturing Delay | Posted 10/31/2017 Updated 10/08/2026 |
| Morphine Sulfate, Injection, 4 mg/1 mL Syringes (NDC 0409-1891-01) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted 10/31/2017 Updated 10/08/2026 | |
| Morphine Sulfate, Injection, 10 mg/1 mL Syringes (NDC 0409-1893-01) | Hospira, Inc., a Pfizer Company | Current Unavailable |
Discontinuation of the manufacture of the drug | Discontinuation of the manufacture of the drug | Posted 10/31/2017 Updated 10/08/2026 |
| Morphine Sulfate, Injection, 50 mg/1 mL (NDC 0409-1896-20) | Hospira, Inc., a Pfizer Company | Current Unavailable |
Other | Next Delivery: January 2027; Estimated Recovery: March 2027; Shortage per Manufacturer: Manufacturing Delay | Posted 10/31/2017 Updated 10/08/2026 |
| Morphine Sulfate, Injection, 50 mg/1 mL (NDC 0409-2022-01) | Hospira, Inc., a Pfizer Company | Current Unavailable |
Other | Next Delivery: January 2027; Estimated Recovery: March 2027; Shortage per Manufacturer: Manufacturing Delay | Posted 10/31/2017 Updated 10/08/2026 |
| Morphine Sulfate, Injection, 5 mg/10 mL (0.5 mg/mL) (NDC 0409-3814-12) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted 10/31/2017 Updated 10/08/2026 | |
| Morphine Sulfate, Injection, 10 mg/10 mL (1 mg/mL) (NDC 0409-3815-12) | Hospira, Inc., a Pfizer Company | Current Available |
— | Posted 10/31/2017 Updated 10/08/2026 | |
| Mitigo, Injection, 200 mg/20 mL (NDC 66794-160-02) | Piramal Critical Care Inc. | Current Available |
— | Posted 10/31/2017 Updated 09/15/2026 | |
| Mitigo, Injection, 500 mg/20 mL (NDC 66794-162-02) | Piramal Critical Care Inc. | Current Available |
— | Posted 10/31/2017 Updated 09/15/2026 |
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